Social connection and stress: what the evidence says (2026)
The studies behind the grade
meta-analytic review of prospective studies · 148 studies, 308,849 participants · adults
These figures come from studies that followed large groups of people over time. They show an association, not proof that the intervention causes the result.
meta-analysis of RCTs · 45 RCTs · mostly non-clinical adult samples; mindfulness apps
These figures come from randomized trials, the strongest test of cause and effect. They describe the people who were studied; whether they apply to you is a question for your doctor.
What it costs
- Foundation: Free community + meditation app · $0
- Measured: + therapy platform · ~$50/mo
- Concierge: + clinical psychologist · Bundled
Costs are the Protocol's cost notes for each tier.
Sources
- Holt-Lunstad J et al. (2010). Social relationships and mortality risk: a meta-analytic review. PLoS Med. Verified September 2026
- Linardon J et al. (2024). The efficacy of mindfulness apps on symptoms of depression and anxiety: an updated meta-analysis of randomized controlled trials. Clin Psychol Rev. Verified September 2026
A grade describes the quality of the research. It is not a treatment recommendation. Talk to your doctor about what's right for you.
Evidence, compared. Not medical advice. Talk to your doctor about what's right for you.
Common questions
- What does the grade mean?
How strong the research is, on the published YL360 Methodology scale. Grade A: the evidence is clear. Grade C: the evidence is thin or mixed. The grade rates the studies, not you.
- Does a higher grade mean a bigger benefit?
No. The grade rates the quality of the evidence. The studies listed show what kind of research it is, how many people were studied, and who they were. A Grade A with a modest effect is common.
- Where do the costs come from?
From the YL360 Protocol's cost note for each tier. Prices on comparison pages carry their own verified dates.
- Is Social connection and stress worth it, then?
That depends on your age, your risk and your budget, and it's a conversation with your doctor. This page gives you the evidence and the price so you walk in prepared.
- Is this medical advice?
No. It's evidence, compared. Talk to your doctor about what's right for you.