Biological age tests: what the evidence says (2026)
The studies behind the grade
systematic review and meta-analysis of cohorts · 41,607 · adults in research cohorts
These figures come from studies that followed large groups of people over time. They show an association, not proof that the intervention causes the result.
prospective cohort comparison of 14 clocks vs 174 outcomes · 18,859 (Generation Scotland) · adults, Generation Scotland
What it costs
- FoundationNot in this tier
- Measured: TruDiagnostic · $250/yr
- Concierge: Bundled · Bundled
Costs are the Protocol's cost notes for each tier.
Sources
- Fransquet PD et al. (2019). The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis. Clin Epigenetics. Verified September 2026
- Christos Mavrommatis et al. (2025). An unbiased comparison of 14 epigenetic clocks in relation to 174 incident disease outcomes. Nat Commun. Verified September 2026
A grade describes the quality of the research. It is not a treatment recommendation. Talk to your doctor about what's right for you.
Evidence, compared. Not medical advice. Talk to your doctor about what's right for you.
Common questions
- What does the grade mean?
How strong the research is, on the published YL360 Methodology scale. Grade A: the evidence is clear. Grade C: the evidence is thin or mixed. The grade rates the studies, not you.
- Does a higher grade mean a bigger benefit?
No. The grade rates the quality of the evidence. The studies listed show what kind of research it is, how many people were studied, and who they were. A Grade A with a modest effect is common.
- Where do the costs come from?
From the YL360 Protocol's cost note for each tier. Prices on comparison pages carry their own verified dates.
- Is Biological age tests worth it, then?
That depends on your age, your risk and your budget, and it's a conversation with your doctor. This page gives you the evidence and the price so you walk in prepared.
- Is this medical advice?
No. It's evidence, compared. Talk to your doctor about what's right for you.